Summary
- Id: L7N695
- Locus: PE05_MYCTU
- Protein Moltype: AA
- Topology: linear
- Definition: PE family immunomodulator PE5
- Organism: Mycobacterium tuberculosis H37Rv
- Division: BCT
- Update Date: 14-May-23
- Create Date: 02-Nov-16
Number of amino acids:
Molecular weight:
Theoretical pI:
Amino acid composition:
Total number of negatively charged residues (Asp + Glu):
Total number of positively charged residues (Arg + Lys):
Atomic composition:
Formula:
Total number of atoms:
Estimated half-life: Instability index: Aliphatic index:
Grand average of hydropathicity (GRAVY):
Taxonomy:
Sequence:
![ProtScale graph]()
Prediction of subcellular localization using TBpred
Prediction of Signal Peptides and their cleavage sites in all domains of life using
SignalP
6.0
![]()
Prediction of transmembrane helices in proteins using TMHMM
- 2.0
Secretory protein prediction result:
Not secretory protein
Prediction of non-classical protein secretion using SecretomeP-2.0
Non-classical secretory protein prediction result:
Non-classical secretory protein
Protein function prediction using DeepGOPlus
Homology between L7N695 and H.
sapiens proteins (GRCh38.p14)
Toxicity prediction using Toxinpred
2
MHC-I and MHC-II binding prediction using NetMHCpan-4.1
and NetMHCIIpan-4.0
Secondary Structure of Protein (
DSSP,
NACCESS,
NetSurfP-3.0
)
Homology proteins in MERITS
Molecular weight:
Theoretical pI:
Amino acid composition:
Total number of negatively charged residues (Asp + Glu):
Total number of positively charged residues (Arg + Lys):
Atomic composition:
Formula:
Total number of atoms:
Estimated half-life: Instability index: Aliphatic index:
Grand average of hydropathicity (GRAVY):
Taxonomy:
Sequence:
Using the scale Hydropath.
/ Kyte & Doolittle, the individual values
for the 20 amino acids are:
ProtScale output for L7N695
Subcellular Location
Prediction of subcellular localization using TBpred
| Final Predicted Class | Cytoplasmic | Integral Membrane | Secreted | Attached to Membrane |
|---|
Prediction of Signal Peptides and their cleavage sites in all domains of life using
SignalP
6.0
| Prediction Result |
OTHER | Sec/SPI (Signal Peptide) | Sec/SPII (Lipoprotein signal peptide) | Tat/SPI(TAT signal peptide) | Tat/SPII (TAT Lipoprotein signal peptide) | Sec/SPIII (Pilin-like signal peptide) | Cleavage Site Position | Probability |
|---|
Plot of the predicted labels and probabilities of the sequence
Prediction of transmembrane helices in proteins using TMHMM
- 2.0
| len | ExpAA | First60 | PredHel | Topology |
|---|
Secretory protein prediction result:
Not secretory protein
Prediction of non-classical protein secretion using SecretomeP-2.0
| Network 1 | Network 2 | Network 3 | SecP score |
|---|
Non-classical secretory protein prediction result:
Non-classical secretory protein
Protein function prediction using DeepGOPlus
Cellular Component
Molecular Function
Biological Process
Homology between L7N695 and H.
sapiens proteins (GRCh38.p14)
Toxicity prediction using Toxinpred
2
MHC-I and MHC-II binding prediction using NetMHCpan-4.1
and NetMHCIIpan-4.0
MHC-I binding prediction result
Allele: HLA-A*01:01, high binders (%rank_EL<0.5): , weak binders (%rank_EL<2): , peptides:
Allele: HLA-A*02:01, high binders (%rank_EL<0.5): , weak binders (%rank_EL<2): , peptides:
Allele: HLA-A*03:01, high binders (%rank_EL<0.5): , weak binders (%rank_EL<2): , peptides:
Allele: HLA-A*24:02, high binders (%rank_EL<0.5): , weak binders (%rank_EL<2): , peptides:
Allele: HLA-B*07:02, high binders (%rank_EL<0.5): , weak binders (%rank_EL<2): , peptides:
MHC-II binding prediction result
Allele: DRB1_0101, high binders (%rank_EL<1): , weak binders (%rank_EL<5):
Allele: HLA-DPA10103-DPB10201, high binders (%rank_EL<1): , weak binders (%rank_EL<5):
Allele: HLA-DQA10102-DQB10501, high binders (%rank_EL<1): , weak binders (%rank_EL<5):
Allele: H-2-IAb, high binders (%rank_EL<1): , weak binders (%rank_EL<5):
Secondary Structure of Protein (
DSSP,
NACCESS,
NetSurfP-3.0
)
DSSP result
| Position | Amino acid | Structure | Structure details | ACC | TCO | KAPPA | ALPHA | PHI | PSI | X-CA | Y-CA | Z-CA |
|---|
NACCESS result
| Position |
All-atoms | Total-Side | Main-Chain | Non-polar | All-polar | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| ABS | REL | ABS | REL | ABS | REL | ABS | REL | ABS | REL | |